Wednesday, September 23, 2026  ·  Hudson, Ohio  ·  Barboursville, W.Va.
Aesthetic medicine, explained by the physicians who practice it — from Serene Med Spa

Melasma and Hyperpigmentation: What Actually Helps, What Makes It Worse, and How to Keep It Controlled

Melasma is managed, not cured. Dr. Robin Arora explains which creams, peels and gentle procedures help, and why aggressive lasers can make it darker.

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Illustration for an article on melasma and hyperpigmentation treatment at Serene Med Spa
Illustration for an article on melasma and hyperpigmentation treatment at Serene Med Spa

“I tried a laser and it came back darker.” I hear some version of that sentence more often than I would like, and it almost always involves melasma. It is a condition where the instinct to treat hard and fast works against you.

My goal in this article is to set expectations clearly. Melasma can usually be lightened a great deal and kept under control, but it is a chronic condition with a strong tendency to return. Below I’ll cover how to recognize it, what makes it worse, which treatments have the best support, and how we approach it at our Hudson and Barboursville locations.

Melasma versus other dark spots

Hyperpigmentation is an umbrella term for any area of skin that is darker than its surroundings. Under that umbrella sit several different conditions:

The distinction matters because a treatment that clears a sunspot in one session can inflame melasma and deepen it. That is why I examine the pattern, and sometimes use a Wood’s lamp, before recommending anything.

Why melasma happens and what triggers it

We don’t fully understand melasma, but several drivers are well established. Hormones play a clear role, which is why it often appears during pregnancy or with birth control pills or hormone therapy. Genetics matter, since it frequently runs in families. And light is the major accelerator: ultraviolet rays, and also visible light and heat, stimulate the overactive pigment cells.

Common things that make melasma worse include:

The foundation: protection and prescription-strength topicals

Before any procedure, I want a patient’s skin on a consistent home regimen for several weeks. This part of treatment does the heavy lifting.

  1. Daily tinted mineral sunscreen. Tinted formulas with iron oxides block visible light as well as UV. For melasma, this is the single most important habit.
  2. Hydroquinone. It remains the most studied lightening agent. It is typically used in cycles rather than indefinitely, under medical guidance, because long-term uninterrupted use can cause problems such as ochronosis, a rare bluish-gray darkening.
  3. Combination creams. A triple-combination cream containing hydroquinone, a retinoid and a mild steroid is FDA-approved for short-term treatment of moderate to severe facial melasma.
  4. Non-hydroquinone agents such as azelaic acid, tranexamic acid serums, kojic acid, niacinamide and vitamin C are useful for maintenance and for people who cannot use hydroquinone.

Medical-grade systems like Obagi are built around this approach. Oral tranexamic acid has shown promise for melasma in studies, but it is a prescription medication used off-label, with blood-clot considerations, so it is something to discuss at a consultation and is not right for everyone.

In-office treatments: gentle and gradual wins

Once the skin is prepared, procedures can speed things up. The theme is low heat and low inflammation.

What I avoid for most melasma: aggressive IPL, deep ablative resurfacing and high-heat treatments. They may lighten the skin briefly, but the inflammation often triggers rebound pigment that is darker than where you started. Our hyperpigmentation treatment plans are designed with that risk in mind.

Who should wait or take a different path

Melasma treatment should be modified or delayed if you are pregnant or breastfeeding, since many lightening agents and procedures are not appropriate then. People who cannot commit to daily sun protection are unlikely to hold results. And any patch that is changing quickly, is raised, or looks different from typical melasma should be evaluated by a dermatologist to rule out other diagnoses.

Frequently asked questions

Can melasma be cured permanently?

Not at this time. Melasma can be lightened substantially and kept quiet, but it tends to return with sun, heat or hormonal changes. Most people do best with a long-term maintenance routine.

Why did my melasma get worse after a laser or IPL?

Heat and inflammation can stimulate overactive pigment cells, causing rebound darkening. That is why melasma usually calls for gentle treatments and a prepared skin regimen first.

How long does it take to see improvement?

With consistent topicals and sun protection, many people notice lightening within two to three months. Procedures can add to that, but patience is part of the process.

Does melasma go away after pregnancy?

Sometimes it fades on its own within months after delivery, and sometimes it persists. We usually wait until after pregnancy and breastfeeding to start active treatment.

Build a melasma plan that lasts

At Serene Med Spa, treatments are performed or supervised by trained medical professionals under my oversight, and melasma plans are always individualized. Schedule a complimentary, no-commitment consultation to talk through your triggers, your skin type and a realistic timeline.

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References: Grimes PE. Melasma: etiologic and therapeutic considerations. Archives of Dermatology. 1995. · Kligman AM, Willis I. A new formula for depigmenting human skin. Archives of Dermatology. 1975. · U.S. Food and Drug Administration. Prescribing information for fluocinolone acetonide, hydroquinone and tretinoin cream (Tri-Luma). · American Academy of Dermatology. Melasma: diagnosis and treatment. aad.org.

This article is for general information only and is not medical advice. Treatments are provided only after consultation and evaluation by a licensed provider. Individual results vary.

Dr. Robin Arora, MD
About the authorDr. Robin Arora, MD, MBA is the founder and medical director of Serene Med Spa and a Biote Certified Provider. He is board-certified in internal medicine, nephrology and hypertension, and addiction medicine, and in aesthetic medicine through the American Academy of Aesthetic Medicine (AAAM).

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